26 October 2009
This Wednesday, October 28th, the Applied Statistics workshop will welcome Eric Tchetgen Tchetgen, Assistant Professor of Epidemiology at Harvard School of Public Health, presenting his work titled "Doubly robust estimation in a semi-parametric odds ratio model." Eric has provided the following abstract for the paper:
We consider the doubly robust estimation of the parameters in a semi-parametric conditional odds ratio model characterizing the effect of an exposure in the presence of many confounders. We develop estimators that are consistent and asymptotically normal in a union model where either a prospective baseline density function or a retrospective baseline density function is correctly specified but not necessarily both. The case of a binary outcome is of particular interest, then our approach yields a doubly robust locally efficient estimator in a semi-parametric logistic regression model For general types of outcomes, we provide a strategy to obtain doubly robust estimators that are nearly locally efficient We illustrate the method in a simulation study and an application in statistical genetics. Finally, we briefly discuss extensions of the proposed method to the semi-parametric estimation of a parameter indexing an interaction between two exposures on the logistic scale, as well as extensions to the setting of a time-varying exposure in the presence of time-varying confounding.
The Applied Statistics workshop meets each Wednesday in room K-354, CGIS-Knafel (1737 Cambridge St). We start at 12 noon with a light lunch, with presentations beginning around 12:15 and we usually wrap up around 1:30 pm. We hope you can make it.